Inhibitory Effect of Amantadine Hydrochloride on Bovine Virus Diarrhea and SF-4 Viruses
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Authors
Krishnamurti, P.V.
Little, M.G.
Mohanty, S.B.
Advisors
Department
Keywords
Savannah (Ga.)
Chatham County (Ga.)
African American universities and colleges--Georgia—Savannah
Viruses
Chatham County (Ga.)
African American universities and colleges--Georgia—Savannah
Viruses
Issue Date
2016-06-09
Type
Article
Language
en_US
Description
This article appeared in the Faculty Research Bulletin. Begun in 1954, the Faculty Research Edition of the Savannah State College Bulletin was initiated to encourage and publish studies relating to the institution and the fields of special interest of faculty and staff. It contains pure research as well as creative writing. It is primarily a medium for the faculty of SSC, but scholarly papers from other faculties are accepted. Manuscripts that have already been published or accepted for publication in other journals are not included.
Other Titles
Abstract
Certain myxoviruss and several strains of human influenza and parainfluenza viruses are inhibited by amantadine hydrochloride (1-adamantanamine hydrochloride) both in vitro and in vivo. 1, 2, 5 The evaluation of amantadine in the prevention of influenza in humans has been discussed. Other viruses, such as rubella, pseudorabies, and fowl plague viruses are also sensitive to this drug.3, 4 Recently, the drug was shown to inhibit murine sarcoma viruses in cell cultures.
The effect of amantadine hydrocloride on the multiplication
of bovine virus diarrhea (BVD) and SF-4 (bovine myxovirus
parainfluenza-3) viruses in primary bovine embryonic kidney
(BEK) cell culture are presented in this report.